Differentiating Cancerous Versus Benign Kidney Tumors
Tumors of the kidney are being identified at smaller sizes and earlier stages than years previous due to the wide spread use 的 CT and MRI scanning (see Figure 1). As a result, this has provided urologists with the opportunity to achieve higher success rates in curing patients with kidney tumors. Despite earlier diagnosis, however, CT and MRI scans are unable to differentiate between benign (i.e. not cancerous) versus cancerous tumors. Furthermore, up to 30% 的 these small kidney tumors that are surgically removed are later found to be benign. Although a needle biopsy is an option for preoperative diagnosis of such small kidney tumors, it carries the risk of bleeding, infection, transfusion and more importantly the risk of tumor spread. This highlights the importance in exploring efforts at improving the diagnostic accuracy 的 kidney tumors with preoperative imaging tools.
图1。 CT scan demonstrating a solid 3.5cm kidney tumor (arrows) arising within the right kidney. The nature 的 this mass (i.e. benign vs. cancerous) cannot be differentiated based on CT scan findings.
One set of imaging technologies that may hold promise is that 的 optical imaging such as Fiberoptic Confocal Endomicroscopy (Figure 2)
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图2。 Comparison 的 confocal laser endomicroscopy (CLE) image and standard histology. Note the similarity in the cellular structure and organization.